International Journal of Peptides

Natural Peptides with Potential Applications in Drug Development, Diagnosis, and/or Biotechnology


Publishing date
20 Jul 2012
Status
Published
Submission deadline
02 Mar 2012

1Laboratory of Molecular Pharmacology, Department of Pharmacology, Universidade Federal de São Paulo (Medical School of São Paulo), São Paulo, SP, Brazil

2Infectiologie Animale et Santé Publique (CEA/iBiTecS/SPI/LIAS), CEA de Saclay, Bt 152, 91191 Gif-sur-Yvette Cedex, France

3Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama–shi, Toyama, Japan


Natural Peptides with Potential Applications in Drug Development, Diagnosis, and/or Biotechnology

Description

Natural peptides exert their biological activities via different types of interactions regarding variable targeted tissues, cells, membranes, receptors, ion channels, enzymes, associated to central and/or vital physiological processes: cell integrity, central and/or peripheral nervous system, muscles, or blood circulation, and so on. In addition, in most cases these recognition/interaction are highly specific, and among the more specific natural ligands are animal toxins. For this reason, animal toxins constitute unique molecular probes in identifying and studying the targets they recognize. Identification and characterization of toxins, associated with studies for determination of their mechanism of action, have not only complemented our understanding on the mechanisms of toxic effects of toxins in envenomation process, but it has also contributed to make a bridge with our current knowledge about the physiological functioning of the cells. In some cases, these studies have also opened new perspectives for the use of these venom components in biomedicine, as it has been described for a number of natural toxins, especially proteins, oligopeptides, and peptides.

Investigators are invited to contribute with original research and/or review articles on this area, specifically those exploiting the mechanism of action and the structure-activity aspects of natural peptides. Potential topics include, but are not limited to:

  • Characterization of novel and original natural peptides with desirable description of target(s) and/or mechanism(s) of action
  • Well-known natural peptides with unexpected target(s) and/or mechanism(s) of action
  • Natural peptides with mammal endogenous correlates
  • Natural peptides acting on vital physiological machinery with potential application as therapeutics
  • Use of natural peptides to describe novel physiological pathways/mechanism of action
  • Manuscripts exploiting the use of natural peptides in biotechnology or therapy, as drug or as model for the development of drug
  • Structure-function relationship of natural peptides

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijpep/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 757838
  • - Editorial

Natural Peptides with Potential Applications in Drug Development, Diagnosis, and/or Biotechnology

Mirian A. F. Hayashi | Frédéric Ducancel | Katsuhiro Konno
  • Special Issue
  • - Volume 2012
  • - Article ID 249827
  • - Review Article

A Meta-Analysis of the Therapeutic Effects of Glucagon-Like Peptide-1 Agonist in Heart Failure

Mohammed Munaf | Pierpaolo Pellicori | ... | Kenneth Wong
  • Special Issue
  • - Volume 2012
  • - Article ID 965238
  • - Review Article

Antimicrobial Peptides as Infection Imaging Agents: Better Than Radiolabeled Antibiotics

Muammad Saeed Akhtar | Muhammad Babar Imran | ... | Abubaker Shahid
  • Special Issue
  • - Volume 2012
  • - Article ID 781785
  • - Research Article

Pyrazinamide Effects on Cartilage Type II Collagen Amino Acid Composition

Larysa B. Bondarenko | Valentina M. Kovalenko
  • Special Issue
  • - Volume 2012
  • - Article ID 731293
  • - Research Article

Molecular Cloning and Sequence Analysis of the cDNAs Encoding Toxin-Like Peptides from the Venom Glands of Tarantula Grammostola rosea

Tadashi Kimura | Seigo Ono | Tai Kubo
  • Special Issue
  • - Volume 2012
  • - Article ID 532519
  • - Review Article

Platelet-Rich Plasma Peptides: Key for Regeneration

Dolores Javier Sánchez-González | Enrique Méndez-Bolaina | Nayeli Isabel Trejo-Bahena
  • Special Issue
  • - Volume 2012
  • - Article ID 124163
  • - Research Article

Diverse Effects of Glutathione and UPF Peptides on Antioxidant Defense System in Human Erythroleukemia Cells K562

Ceslava Kairane | Riina Mahlapuu | ... | Ursel Soomets

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