Statistical Analysis of Efficient Unbalanced Factorial Designs for Two-Color Microarray Experiments

Table 3

EGLS inference on overall importance of fixed effects for ID_REF #30 based on REML versus ANOVA (type III quadratic forms) for estimation of variance components using output from SAS PROC MIXED (code in Figure 3).

		Type 3 tests of fixed effects using REML			Type 3 tests of fixed effects using ANOVA
Effect	Num DF^*	Den DF^*	F value	Pr > F^†	Den DF^*	F value	Pr > F^†
Inoc	2	5.28	3.12	0.1273	6.36	3.48	0.0954
Time	2	17.8	2.81	0.0870	22.8	3.27	0.0563
Inoc^*time	4	5.28	1.26	0.3893	6.36	1.38	0.3392
Dye	1	5.43	2.27	0.1879	5.15	2.19	0.1973

^*Num Df = numerator degrees of freedom; Den DF = denominator degrees of freedom.
^†P-value.