Methodology Report

How to Group Genes according to Expression Profiles?

Table 2

Estimated mean, standard error, and lower (LB) and upper boundaries (UB) of a 95% confidence interval for the bias for each method applied to the estimation of the number of clusters in the simulated datasets. True number of clusters: . Clustering algorithm: average linkage.

MethodMean biasStandard errorLB (95%)UB (95%)

HOPACHm7.351.07 5.259.45
HOPACHc7.281.07 5.189.38
CH0.440.10 0.240.64
Gap0.350.10 0.150.55
Silh0.340.10 0.140.54
H0.220.10 0.020.42
CCCm0.160.10−0.040.36
CCC0.160.10−0.040.36
gDGC0.030.10−0.170.23
MClust0.010.10−0.190.21