Methodology Report

How to Group Genes according to Expression Profiles?

Table 5

Estimated means, standard error, and lower (LB) and upper boundaries (UB) of a 95% confidence interval for the bias for each combination of method ( ) and number of genes ( ). The table is sorted in descending order of bias within each level of . True number of clusters: . Clustering algorithm: complete linkage.

Mean biasStandard errorLB (95%)UB (95%)

HOPACHm10014.932.0810.8519.01
HOPACHc10011.142.08 7.0515.22
Gap100 3.110.22 2.693.54
H100 1.930.22 1.512.35
CH100 0.680.22 0.261.10
Silh100 0.450.22 0.030.88
CCC100 0.160.22−0.260.58
CCCm100 0.160.22−0.260.58
gDGC100 0.050.22−0.380.47
MClust100−0.050.22−0.470.38
HOPACHm300 8.162.08 4.0812.24
H300 6.410.22 5.996.83
Gap300 4.770.22 4.355.20
HOPACHc300 3.952.08−0.138.04
CH300 0.110.22−0.310.54
gDGC300 0.090.22−0.330.51
Silh300 0.070.22−0.350.49
CCC300 0.020.22−0.400.45
CCCm300 0.020.22−0.400.45
MClust300−0.020.22−0.450.40