Review Article

Heat Shock Protein: Hard Worker or Bad Offender for Gastric Diseases

Figure 2

Proteomic dissection for potential biomarkers for disease progression and carcinogenesis. (a) Helicobacter pylori-associated chronic superficial gastritis was significantly associated with attenuated levels of HSP70 as identified in previous publication [10]. (b) Biopsied tissues obtained from diverse stage of H. pylori-associated gastric diseases were used for proteomic analysis. (c) On individual analysis after (b), significant correlation was noted between the increased spot density of HSP27 and the progression of H. pylori-associated gastric disease, confirming previous publications that HSP27 can be one of potential biomarker for H. pylori-associated gastric diseases. (d) MAPKK can be another candidate telling the progression of H. pylori-associated gastric diseases.
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