Protein Biomarkers for the Early Detection of Breast Cancer

Table 1

Current promising biomarkers for the detection of breast cancer.

Name of biomarker	Technology used for discovery	Type	Reference
RS/DJ-1	Humoral response	autoantibody	[36]
p53	Humoral response	autoantibody	[44–47]
HSP60	Humoral response	autoantibody	[48, 49]
HSP90	Humoral response	autoantibody	[50, 51]
Mucin-related	Humoral response	autoantibody	[49, 52–54]
CA 15-3	Serum profiling	serum protein	[55, 56]
RS/DJ-1	Serum profiling	serum protein	[36]
HER-2/neu	Serum profiling	serum protein	[72]
α-2-HS-glycoprotein	Nipple aspirate fluid profiling	Ductal protein	[90]
Lipophilin B	Nipple aspirate fluid profiling	Ductal protein	[90]
beta-globin	Nipple aspirate fluid profiling	Ductal protein	[90]
Hemopexin	Nipple aspirate fluid profiling	Ductal protein	[90]
Vitamin D-binding protein	Nipple Aspirate Fluid Profiling	Ductal protein	[90]