Glycoproteomics-Based Identification of Cancer Biomarkers

Table 2

A partial list of lectins commonly used for enrichment of glycoproteins/glycopeptides.

Lectin	Specificity
Aleuria Aurantia Lectin (AAL)	Fucα1-6 GlcNAc, Fucα1-3(Galβ1-4)GlcNAc
Concanavalin A (Con A)	High-Mannose, Manα1-6(Manα1-3)Man
Erythrina Cristagalli Lectin (ECA)	Galβ1-4GlcNAc
Hippeastrum Hybrid Lectin (HHL, AL)	High-Mannose, Manα1-3Man, Manα1-6Man
Jacalin	Galβ1-3GalNAc, GalNAc
Lens Culinaris Agglutinin (LCA)	Fucα1-6 GlcNAc, α-D-Glc, α-D-Man
Maackia Amurensis Lectin (MAL)	Siaα2-3Galβ1-4GlcNAc
Peanut Agglutinin (PNA)	Galβ1-3GalNAc
Phaseolus vulgaris Leucoagglutinin (PHA-L)	Tri/tetra-antennary complex-type N-glycan
Sambucus Nigra Lectin (SNA, EBL)	Siaα2-6Gal/GalNAc
Ulex Europaeus Agglutinin-I (UEA-I)	Fucα1-2Galβ1-4GlcNAc
Wheat Germ Agglutinin (WGA)	Chitin oligomers, Sia