Research Article

Cathepsin D Expression in Colorectal Cancer: From Proteomic Discovery through Validation Using Western Blotting, Immunohistochemistry, and Tissue Microarrays

Table 1

Clinico-pathological details of patients.

Patient 1Patient 2Patient 3Patient 4Patient 5Patient 6Patient 7Patient 8

Site of primary tumorRecto-sigmoidCaecumAscending colonSigmoid colonRecto-sigmoidCaecumAscending colonRecto-sigmoid
Degree of differentiationModeratelyPoorlyPoorlyModeratelyModeratelyPoorlyModeratelyWell
Age at diagnosis*5871638150545865
GenderFMFMMMFM
TNM stage of primary tumor23323332
LM diagnosis**MetSynchSynchSynchSynchSynchSynchSynch
Liver involvement***Solitary <25%Multiple 25–50%Multiple >50%Multiple 25–50%Three 25–50%Multiple >50%Multiple <25%Four
<25%

*Mean age at primary tumor diagnosis: 62.9 ± 10 (mean ± SD).
**Met: Metachronous diagnosis, Synch: Synchronous diagnosis.
***Number of liver metastases (multiple: too many to count), plus percentage of liver involvement.