Functional Proteomic Profiling of Phosphodiesterases Using SeraFILE Separations Platform
Figure 1
The cAMP hydrolysis activity in clarified rat brain homogenate (RBH), (a), and bovine brain homogenate (BBH), (b), proteomes. The cAMP hydrolysis activity was measured by using dilutions of the clarified homogenates in the absence of cGMP (solid black) or in presence of 25 μM cGMP (solid gray) or 50 μM cGMP (dashes).