The Application of a Three-Step Serum Proteome Analysis for the Discovery and Identification of Novel Biomarkers of  Hepatocellular Carcinoma

<table>Representative chromatogram during fractionation by RP-HPLC of serum samples in which highly abundant proteins were immunodepleted. Concentrated immunodepleted samples were directly loaded onto the RP column and 40 fractions were collected every 0.5 min from 19.1 to 39.1 min ((a) arrow) as described in the experimental procedures. Among them, a total of 22 fractions were processed for SDS-PAGE analysis (b).</table>

International Journal of Proteomics

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Figure 3

Figure 3: The Application of a Three-Step Serum Proteome Analysis for the Discovery and Identification of Novel Biomarkers of  Hepatocellular Carcinoma 

Figure 3 | The Application of a Three-Step Serum Proteome Analysis for the Discovery and Identification of Novel Biomarkers of  Hepatocellular Carcinoma 