Research Article

Ethanol Exposure Alters Protein Expression in a Mouse Model of Fetal Alcohol Spectrum Disorders

Figure 4

Immunolocalization of serotransferrin to the heart, branchial arches and somites with alcohol treatment. Serotransferrin immunostaining (Tf-im) (a,b,c,d) and triosephosphate isomerase immunostaining (Tpi1-im) (e,f) are increased in alcohol-treated embryos at E10.25. Tf-im consistently localized to the heart (dotted region), branchial arch 1 (BA1) and somites (somites) of alcohol-treated embryos (a) relative to control (b). High magnification of the dotted region is shown in (c) (Alcohol) and (d) (Control). Tpi1-im was diffusely increased in alcohol-treated embryos (e) relative to control (f), but the staining pattern was less consistent.
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