An Internal Standard-Assisted Synthesis and Degradation Proteomic Approach Reveals the Potential Linkage between VPS4B Depletion and Activation of Fatty Acid β-Oxidation in Breast Cancer Cells

Table 1

Increased protein expression is mostly due to increased protein synthesis in SKBR3_shVPS4B cells.

	Number of proteins*	Percentage (%)
Increased synthesis only	21	63.6
Decreased degradation only	3	9.1
Both	3	9.1
Other	6	18.2

*Number of proteins was calculated from 33 proteins with increased relative abundance (SKBR3_shVPS4B versus SKBR3 ratio >1.5) at 24 hr.