Issues and Applications in Label-Free Quantitative Mass Spectrometry
Figure 4
Volcano plots of all 4,112 Caco-2/HT29-MTX cell proteins with Log2 fold-change in expression on the x axis and value on the y axis. (a) 20 nm AgNP-citrate 12.5 μg/mL, 3 h effect. (b) 20 nm AgNP-citrate 12.5 μg/mL, 24 h effect. Blue ellipses surround significantly decreased proteins; red ellipses are increased proteins. (c) Venn diagram illustrates that AgNP-mediated effects are unique at the two time points, and little overlap in biological effect occurs.
