Molecular Integrity of Mitochondria Alters by Potassium Chloride

Figure 9

Transmission electron microscopic analysis of mitochondrial surface before and after the treatment of KCl showed mitochondrial swelling, altered morphology of cristae, and disruption in outer mitochondrial membrane after KCl treatment. (a) Ultrastructure of control mitochondria; (b) enlarged micrograph of isolated mitochondria; (c) ultrastructure of KCl treated mitochondria; (d) enlarged micrograph of KCl treated mitochondria; (e) histogram of % of deformed mitochondria of control and KCl treated mitochondrial fraction (percentage is calculated by dividing number of deformed mitochondria by total number of mitochondria). denoted the significance level compared to control.