Advances in Quantitative Mass Spectrometry
1Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA
2Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA
3Mark Wainwright Analytical Centre, The University of New South Wales, Sydney, NSW, Australia
Advances in Quantitative Mass Spectrometry
Description
Quantitative mass spectrometry is designed for accurate quantification of proteins and peptides in a complex biological sample, leading to biomarker discovery and validation. A wide variety of approaches have been developed toward the identification and quantification of proteins with improved quantitative precision, including label-free protein quantification technology and candidate-based multiple-reaction-monitoring approach. The key to successfully measure protein biomarker candidates relies on increased sensitivity and precision. We invite authors to submit original research and review articles that explore aspects of new methodology development in quantitative mass spectrometry and/or applications of quantitative mass spectrometry in biomarker development. Potential topics include, but are not limited to:
- Development of novel and effective methods for mass-spectrometry-based protein quantification
- Development of new strategies to identify and quantify protein biomarkers
- Utilization of high-resolution mass spectrometry for quantitative protein analysis
- New mass-spectrometry-based assay development for biomarker validation
- Data management and new strategies for data analysis
Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijpro/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: