Polymers for Fabricating Nerve Conduits

Table 2

Summary of structural luminal fillers in polymer nerve conduits.

Filler material	Structure	Filler form	Tube material(s) [reference(s)]
Agarose coupled with laminin		Gel rod	PSU [129]
Alginate with or without fibronectin		Gel rod	PHB [99]
Chitosan immobilized with peptides		Electrospun fiber mesh inner layer	Chitosan [25]
Collagen		Aligned fibrils	Collagen [37], Silicone [63]
		Fiber	PGA coated with collagen [90]
		Sponge	PGA coated with collagen [90–93]
		Gel layer	PU [135]
Collagen-GAG		Gel rod	Collagen and silicone [34]
Fibrin		Gel rod	Silicone [60], PLGC [119], PHB [97]
HA		Gel rod	PE [64]
Gelatin		Fiber or gel rod	Gelatin [45]
Matrigel		Gel rod	PTMC-CL [132], PDLLA and PE [65]
SF		Longitudinal aligned fiber	SF [55]
Polyamide		Filament	Silicone [62]
PAN-MA		Electrospun fiber	PSU [130]
PGA		Longitudinal aligned fiber	Chitosan [26]
		Filament	PTMC-CL [133]
PHBV/PLGA blends		Electro-spun mat	PHBV/P(L-D,L)LA/PLGA blends [101]
PLLA		Filament	Silicone and P(L-D,L)LA (75 : 25) [61]
PLGA		Electro-spun fiber mat roll; (LA:GA = 85 : 15)	PSU [131]
		PHEMA inner layer embedded with PLGA microspheres; (LA:GA = 85 : 15)	PHEMA-MMA [68]
		PCL inner layer embedded with PLGA microspheres; (LA:GA = 50 : 50)	PCL [76]
PP		Filament	PAN-PVC [57]