
Growth factor  Polymer  Quantity loaded  Release  Reference 

rhBMP2 and VEGF  Silk  40 μg/mL VEGF 60 μg/mL BMP2  ~15% VEGF after 28 days ~15% BMP2 after 28 days  [147] 

rhBMP2  PEG  50 mg/mL  ~56% after 15 days for glycosylated rhBMP2, ~35% after 15 days for nonglycosylated  [154] 

BMP2  Alginate  Up to 25 μg/mL
 ~85% after 14 days  [46] 

BMP2  Alginate  40 μg/mL  ~98% after 7 days  [25] 

BMP2  Hyaluronic acid  150 μg/mL  Not disclosed  [55] 

BMP2  Hyaluronic acid  150 μg/mL  Not conducted (animal study)  [64] 

BMP2  Chitosan  0.75 mg/mL  Not conducted (animal study)  [79] 

BMP2  Chitosan or hyaluronic acid  0.75 mg/mL  Not conducted (animal study)  [148] 

BMP2  Collagenhydroxyapatite composite PEG  200 μg/mL  ~72% after 3 days, ~95% after 7 days  [149] 

BMP2 and VEGF  Hyaluronic acid  0.01 mg/mL VEGF 0.01 mg/mL BMP2  ~100% after 4 days for fast degrading hydrogels ~100% after 7 days for slow degrading hydrogels (VEGF releasing slightly slower than BMP2)  [49] 

BMP2  Hyaluronic acid  200 μg/mL  ~10% after 24 hours ~25% after 35 days  [66] 

VEGFA and PDGFBB  Alginate  30 μg/mL PDGFBB and/or 3 μg/mL VEGFA_{165}  ~50% VEGF after 24 hours, ~80% after 30 days ~15% PDGFBB after 24 hours, ~75% after 30 days  [155] 

FGF and VEGF  PEG heparin  1 or 5 μg/mL  ~10% after 4 days  [153] 
