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International Journal of Polymer Science
Volume 2012 (2012), Article ID 646578, 14 pages
http://dx.doi.org/10.1155/2012/646578
Research Article

Long-Term Biostability of Pet Vascular Prostheses

1Laboratoire de Physique et Mécanique Textiles, ENSISA, 11 rue des Frères Lumières, 68093 Mulhouse Cedex, France
2Textile Research Unit, High Technology Institute, Hadj Ali Soua, Ksar-Hellal 5070, Tunisia
3Laboratoire de Chimie Organique et Bio-organique, École Nationale Supérieure de Chimie de Mulhouse, Université de Haute Alsace, 68093 Mulhouse, France
4Department of Vascular Surgery, Les Hôpitaux Universitaires de Strasbourg, University of Strasbourg, 67000 Strasbourg, France

Received 22 July 2011; Revised 8 November 2011; Accepted 16 November 2011

Academic Editor: Haojun Liang

Copyright © 2012 Florence Dieval et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

PET Vascular prostheses are susceptible to physical modification and chemical degradation leading sometimes to global deterioration and rupture of the product. To understand the mechanisms of degradation, we studied 6 vascular prostheses that were explanted due to medical complications. We characterized their level of degradation by comparing them with a virgin prosthesis and carried out physicochemical and mechanical analyses. Results showed an important reduction of the fabric’s mechanical properties in specific areas. Moreover, PET taken from these areas exhibited structural anomalies and was highly degraded even in virgin prostheses. These results suggest that vascular prostheses have weak areas prior to implantation and that these areas are much more prone to in vivo degradation by human metabolism. Manufacturing process could be responsible for these weaknesses as well as designing of the compound. Therefore, we suggest that a more controlled manufacturing process could lead to a vascular prosthesis with enhanced lifespan.