Enhancing Antidepressant Effect of Poloxamer/Chitosan Thermosensitive Gel Containing Curcumin-Cyclodextrin Inclusion Complex

Figure 4

Curcumin concentration profile in plasma and hippocampus of male Sprague-Dawley rats after 240 μg/kg intranasal administration of the inclusion complex and the thermoreversible gel and 240 μg/kg intravenous administration of curcumin solution over 8 h.