Peptide–Polymer Conjugates: A Promising Therapeutic Solution for Drug-Resistant Bacteria

Figure 2

Schematic of the preparation of the ALG/HA/COL-AMP wound dressings. (a) The Tet213-conjugated ALG/HA/COL wound dressings were prepared using the chemical reaction between the carboxyl groups and the amino groups on ALG, COL, HA, and Tet213. (b) The slow release of Tet213 due to the cleavage of the amide bond combined into the wound-dressing substrates helps kill bacteria, avoid the unrestrained release of Tet213 at the tissue sites, and excessive dressing changes. Reprinted with permission from ref [84]. Copyright 2019 Elsevier.

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