Case Report

Treatment of Complicated Henoch-Schönlein Purpura with Mycophenolate Mofetil: A Retrospective Case Series Report

Table 3

Treatment protocols and outcomes of patients.

Corticostroid Dose/Route/DurationResponse to corticostroidMycophenolate mofetil (MMF) Dose/DurationResponse to Mycophenolate mofetil (MMF)Mean arterial pressure (mmHg) before treatment by Mycophenolate mofetil (MMF)Mean arterial pressure (mmHg) one week after treatment by Mycophenolate mofetil (MMF)

Case   1Prednisolone 2 mg/kg/d PO for 8 weeksStroid dependency30 mg/kg For 3 weeksSignificant recovery in 48 hours8486
Case   2Prednisolone 2 mg/kg/d PO for 8 weeksStroid dependency30 mg/kg For 6 weeksSignificant recovery in one week7877
Case   3Prednisolone 2 mg/kg/d PO for 8 weeksStroid dependency30 mg/kg For 8 weeksSignificant recovery in one month8080
Case   4Prednisolone 2 mg/kg/d PO for 2 weeksNo response30 mg/kg For 8 weeksSignificant recovery in one month8685
Case  5 Methyl prednisolone 20 mg/kg IV for 3 doses every other day then Prednisolone 2 mg/kg/d for first 4 weeks and 2 mg/kg/every other day for second 4weeksNo response30 mg/kg For 6 monthSignificant recovery of proteinuria but continuation of microscopic hematuria8690
Case   6Prednisolone 2 mg/kg/d PO for first 4 weeks and 2 mg/kg/every other day for second 4weeksStroid dependency30 mg/kg For 8 weeksSignificant recovery in one month7679