(a) Effect of subcutaneous administration of GS on OARSI score in STR/ort mice. Data are represented as median. (b) Effect of subcutaneous administration of GS on Lesion surface/total surface in STR/ort mice. Data are represented as mean ± SE. (c) Effect of subcutaneous administration of GS on n. of viable cells/total cartilage volume in STR/ort mice. Data are represented as mean ± SE. * = versus vehicle (ANOVA). The vehicle group is always statistically different from the naïve 5-month-old group.