Review Article

The Utility of Serum IgG4 Concentrations as a Biomarker

Table 1

IgG4 concentrations, age and complications of more than 3 extrapancreatic lesions in patients with autoimmune pancreatitis and major extrapancreatic lesions.

(male/female)Age, yr Median  (range)IgG4, mg/dL Median  (range)Complications of more than 3 extrapancreatic lesions, (%)

Autoimmune pancreatitis92 (72/20)66 (38–85)545 (4–2970)11(12%)
Mikulicz’s disease41 (31/10)65 (43–82)697 (18–2970)13 (32%)
Sclerosing cholangitis71 (53/18)67 (38–84)500 (4–2970)13 (18%)
Retroperitoneal fibrosis27 (23/4)66 (50–80)1110 (247–2970)12 (44%)
Kidney lesion18 (14/4)67 (56–82)1313 (156–2970)9 (50%)