Are Classification Criteria for IgG4-RD Now Possible? The Concept of IgG4-Related Disease and Proposal of Comprehensive Diagnostic Criteria in Japan

Table 6

Sensitivity and specificity of serum levels of IgG4 in patients with type 1 AIP.

	Cut-off	Sensitivity		Specificity
	mg/dL	n	Median/(range)	n	(vs cancer)
Japan	135
Okazaki et al. [16]		71	80% 410 (3–3670)	101	98%
Okazaki et al [17]		52	73% 505 (43–1540)		NS
Kawa et al. [18]		64	92% 618 (8–2855)	80	98%
Korea	135
Choi et al. [19]		30	73% 473 (10–1764)	76	99%
USA	140
Ghazale et al. [20]		45	76% 550 (16–2890)	135	90%
Raina et al. [21]		26	44% (8–825)	NS
Italy	135
	(focal)	55	66% 267		NS
Frulloni et al. [22]	(diffuse)	32	27% 78