Clinical Study
Cutoff Values of Serum IgG4 and Histopathological IgG4+ Plasma Cells for Diagnosis of Patients with IgG4-Related Disease
Table 4
Sensitivity and specificity of pathological findings for the diagnosis of IgG4-RD.
| | ć | Sensitivity | Specificity |
| | IgG4+/IgG+ > 10% | 100.0% | 33.3% | | IgG4+/IgG+ > 20% | 100.0% | 47.6% | | IgG4+/IgG+ > 30% | 100.0% | 71.4% | | IgG4+/IgG+ > 40% | 94.4% | 85.7% | | IgG4+/IgG+ > 50% | 94.4% | 95.2% | | IgG4+cells/HPF > 10 | 100.0% | 38.1% | | IgG4+cells/HPF > 20 | 97.2% | 42.9% | | IgG4+cells/HPF > 30 | 97.2% | 61.9% | | IgG4+cells/HPF > 40 | 91.7% | 66.7% | | IgG4+cells/HPF > 50 | 86.1% | 71.4% | | Obliterative phlebitis | 54.5% | 100.0% | | Storiform fibrosis | 31.4% | 100.0% | | Eosinophilia | 42.9% | 100.0% | | Fibrosis | 91.4% | 82.4% | | Lymphocytic infiltration | 100.0% | 16.7% |
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