Pathologies Associated with Serum IgG4 Elevation

Table 2

Final diagnosis in patients with elevated serum IgG4 level (>1.35 g/L).

	𝑛 (%)	Mean IgG4 levels (g/L)
		(extremes)
Repeated infections	15 (25.4%)	2.31 (1.37–4.3)
Autoimmune diseases	8 (13.6%)	3.62 (1.38–11.3)
No final diagnosis	8 (13.6%)	1.94 (1.37–2.97)
IgG4-RD	6 (10.1%)	12.64 (2.48−20.6)
Possible IgG4-RD	5 (8.5%)	2.23 (1.56–3.37)
Cancer	4 (6.8%)	2.00 (1.71–2.32)
Primary immune deficiency	4 (6.8%)	1.80 (1.44–2.24)
Interstitial pneumonitis	3 (5%)	5.54 (1.51–12.7)
Cystic fibrosis	2 (3.4%)	4.49 (3.36–5.62)
Erdheim Chester disease	2 (3.4%)	3.05 (2.15–3.94)
Vasculitis	2 (3.4%)	3.68 (3.06–4.30)

IgG4-RD: IgG4-related disease.
Apart from the final diagnostic retained, allergic and atopic manifestations were found in 10 patients (16.9%).