TNF-Alpha in the Locomotor System beyond Joints: High Degree of Involvement in Myositis in a Rabbit Model
Figure 10
In situ hybridization for the demonstration of TNF-alpha mRNA in the muscle tissue. Adjacent sections are shown, one processed with antisense probe (a), the other with sense probe (b). There are reactions in muscle fibers in (a) but not in (b). Arrowheads indicate corresponding muscle fibers in (a) and (b). As verified via examinations of parallel sections processed for morphology, the reactive muscle fibers are infiltrated by inflammatory cells. Certain muscle fibers appear to be unaffected (asterisk).
