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International Journal of Rheumatology
Volume 2012 (2012), Article ID 714321, 11 pages
http://dx.doi.org/10.1155/2012/714321
Review Article

Cardiovascular Risk in Patients with Psoriatic Arthritis

Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong

Received 10 January 2012; Revised 14 February 2012; Accepted 21 February 2012

Academic Editor: George D. Kitas

Copyright © 2012 Tracy Y. Zhu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Y. Alamanos, P. V. Voulgari, and A. A. Drosos, “Incidence and prevalence of psoriatic arthritis: a systematic review,” Journal of Rheumatology, vol. 35, no. 7, pp. 1354–1358, 2008. View at Scopus
  2. D. D. Gladman, R. Shuckett, and M. L. Russell, “Psoriatic arthritis (PSA)—an analysis of 220 patients,” Quarterly Journal of Medicine, vol. 62, no. 238, pp. 127–141, 1987. View at Scopus
  3. N. J. McHugh, C. Balachrishnan, and S. M. Jones, “Progression of peripheral joint disease in psoriatic arthritis: a 5-yr prospective study,” Rheumatology, vol. 42, no. 6, pp. 778–783, 2003. View at Publisher · View at Google Scholar · View at Scopus
  4. D. Kane, L. Stafford, B. Bresniham, and O. FitzGerard, “A prospective, clinical and radiological study of early psoriatic arthritis: an early synovitis clinic experience,” Rheumatology, vol. 42, no. 12, pp. 1460–1468, 2003. View at Publisher · View at Google Scholar
  5. M. J. Peters, I. E. Van Der Horst-Bruinsma, B. A. Dijkmans, and M. T. Nurmohamed, “Cardiovascular risk profile of patients with spondylarthropathies, particularly ankylosing spondylitis and psoriatic arthritis,” Seminars in Arthritis and Rheumatism, vol. 34, no. 3, pp. 585–592, 2004. View at Publisher · View at Google Scholar · View at Scopus
  6. A. M. Tobin, D. J. Veale, O. FitzGerald et al., “Cardiovascular disease and risk factors in patients with psoriasis and psoriatic arthritis,” Journal of Rheumatology, vol. 37, no. 7, pp. 1386–1394, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. R. Ramonda, A. Lo Nigro, V. Modesti et al., “Atherosclerosis in psoriatic arthritis,” Autoimmunity Reviews, vol. 10, no. 12, pp. 773–778, 2011. View at Publisher · View at Google Scholar
  8. K. Wong, D. D. Gladman, J. Husted, J. A. Long, and V. T. Farewell, “Mortality studies in psoriatic arthritis: results from a single outpatient clinic. I. Causes and risk of death,” Arthritis and Rheumatism, vol. 40, no. 10, pp. 1868–1872, 1997. View at Publisher · View at Google Scholar · View at Scopus
  9. F. C. Wilson, M. Icen, C. S. Crowson, M. T. McEvoy, S. E. Gabriel, and H. M. Kremers, “Time trends in epidemiology and characteristics of psoriatic arthritis over 3 decades: a population-based study,” Journal of Rheumatology, vol. 36, no. 2, pp. 361–367, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Shbeeb, K. M. Uramoto, L. E. Gibson, W. M. O'Fallon, and S. E. Gabriel, “The epidemiology of psoriatic arthritis in Olmsted County, Minnesota, USA, 1982-1991,” Journal of Rheumatology, vol. 27, no. 5, pp. 1247–1250, 2000. View at Scopus
  11. M. E. T. Roberts, V. Wright, A. G. S. Hill, and A. C. Mehra, “Psoriatic arthritis. Follow up study,” Annals of the Rheumatic Diseases, vol. 35, no. 3, pp. 206–212, 1976. View at Scopus
  12. C. C. Mok, C. L. Kwok, L. Y. Ho, P. T. Chan, and S. F. Yip, “Life expectancy, standardized mortality ratios, and causes of death in six rheumatic diseases in Hong Kong, China,” Arthritis and Rheumatism, vol. 63, no. 5, pp. 1182–1189, 2011. View at Publisher · View at Google Scholar
  13. B. L. Coulton, K. Thomson, D. P. M. Symmons, and A. J. Popert, “Outcome in patients hospitalised for psoriatic arthritis,” Clinical Rheumatology, vol. 8, no. 2, pp. 261–265, 1989. View at Scopus
  14. C. E. Buckley, C. R. Cavill, G. J. Taylor et al., “Mortality in psoriatic arthritis-a single-center study from the UK,” Journal of Rheumatology, vol. 37, no. 10, pp. 2141–2144, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. Y. Ali, B. D. M. Tom, C. T. Schentag, V. T. Farewell, and D. D. Gladman, “Improved survival in psoriatic arthritis with calendar time,” Arthritis and Rheumatism, vol. 56, no. 8, pp. 2708–2714, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. Y. Alamanos, N. G. Papadopoulos, P. V. Voulgari et al., “Epidemiology of Psoriatic Arthritis in Northwest Greece, 1982-2001,” Journal of Rheumatology, vol. 30, no. 12, pp. 2641–2644, 2003. View at Scopus
  17. O. Ahlehoff, G. H. Gislason, M. Charlot et al., “Psoriasis is associated with clinically significant cardiovascular risk: a Danish nationwide cohort study,” Journal of Internal Medicine, vol. 270, no. 2, pp. 147–157, 2011. View at Publisher · View at Google Scholar
  18. D. D. Gladman, V. T. Farewell, K. Wong, and J. Husted, “Mortality studies in psoriatic arthritis: results from a single outpatient center. II. Prognostic indicators for death,” Arthritis and Rheumatism, vol. 41, no. 6, pp. 1103–1110, 1998. View at Publisher · View at Google Scholar · View at Scopus
  19. D. D. Gladman, “Mortality in psoriatic arthritis,” Clinical and Experimental Rheumatology, vol. 26, no. 5, pp. S62–S65, 2008. View at Scopus
  20. S. Kondratiouk, N. Udaltsova, and A. L. Klatsky, “Associations of psoriatic arthritis and cardiovascular conditions in a large population,” The Permanente Journal, vol. 12, no. 4, pp. 4–8, 2008.
  21. M. Khraishi, D. MacDonald, E. Rampakakis, J. Vaillancourt, and J. S. Sampalis, “Prevalence of patient-reported comorbidities in early and established psoriatic arthritis cohorts,” Clinical Rheumatology, vol. 30, no. 7, pp. 877–885, 2011. View at Publisher · View at Google Scholar
  22. C. Han, D. W. Robinson, M. V. Hackett, L. C. Paramore, K. H. Fraeman, and M. V. Bala, “Cardiovascular disease and risk factors in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis,” Journal of Rheumatology, vol. 33, no. 11, pp. 2167–2172, 2006. View at Scopus
  23. D. D. Gladman, M. Ang, L. Su, B. D. M. Tom, C. T. Schentag, and V. T. Farewell, “Cardiovascular morbidity in psoriatic arthritis,” Annals of the Rheumatic Diseases, vol. 68, no. 7, pp. 1131–1135, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. J. A. Husted, A. Thavaneswaran, V. Chandran et al., “Cardiovascular and other comorbidities in patients with psoriatic arthritis: a comparison with patients with psoriasis,” Arthritis Care and Research, vol. 63, no. 12, pp. 1729–1735, 2011. View at Publisher · View at Google Scholar
  25. A. Jamnitski, I. M. Visman, M. J. L. Peters, M. Boers, B. A. C. Dijkmans, and M. T. Nurmohamed, “Prevalence of cardiovascular diseases in psoriatic arthritis resembles that of rheumatoid arthritis,” Annals of the Rheumatic Diseases, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. H. Brunner, J. R. Cockcroft, J. Deanfield et al., “Endothelial function and dysfunction. Part II: association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension,” Journal of Hypertension, vol. 23, no. 2, pp. 233–246, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. J. Deanfield, A. Donald, C. Ferri et al., “Endothelial function and dysfunction. Part I: methodological issues for assessment in the different vascular beds: a statement by the working group on endothelin and endothelial factors of the European society of hypertension,” Journal of Hypertension, vol. 23, no. 1, pp. 7–17, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. C. Gonzalez-Juanatey, J. Llorca, J. A. Miranda-Filloy et al., “Endothelial dysfunction in psoriatic arthritis patients without clinically evident cardiovascular disease or classic atherosclerosis risk factors,” Arthritis Care and Research, vol. 57, no. 2, pp. 287–293, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. P. C. G. Simons, A. Algra, M. L. Bots, D. E. Grobbee, and Y. Van Der Graaf, “Common carotid intima-media thickness and arterial stiffness: indicators of cardiovascular risk in high-risk patients: the SMART study (Second Manifestations of ARTerial disease),” Circulation, vol. 100, no. 9, pp. 951–957, 1999. View at Scopus
  30. P. Pignoli, E. Tremoli, and A. Poli, “Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging,” Circulation, vol. 74, no. 6, pp. 1399–1406, 1986. View at Scopus
  31. F. Atzeni, P. Sarzi-Puttini, S. Sitia et al., “Coronary flow reserve and asymmetric dimethylarginine levels: new measurements for identifying subclinical atherosclerosis in patients with psoriatic arthritis,” Journal of Rheumatology, vol. 38, no. 8, pp. 1661–1664, 2011. View at Publisher · View at Google Scholar
  32. L. S. Tam, Q. Shang, E. K. Li et al., “Subclinical carotid atherosclerosis in patients with psoriatic arthritis,” Arthritis and rheumatism, vol. 59, no. 9, pp. 1322–1331, 2008. View at Publisher · View at Google Scholar · View at Scopus
  33. C. Gonzalez-Juanatey, J. Llorca, E. Amigo-Diaz, T. Dierssen, J. Martin, and M. A. Gonzalez-Gay, “High prevalence of subclinical atherosclerosis in psoriatic arthritis patients without clinically evident cardiovascular disease or classic atherosclerosis risk factors,” Arthritis Care and Research, vol. 57, no. 6, pp. 1074–1080, 2007. View at Publisher · View at Google Scholar · View at Scopus
  34. O. Kimhi, D. Caspi, N. M. Bornstein et al., “Prevalence and risk factors of atherosclerosis in patients with psoriatic arthritis,” Seminars in Arthritis and Rheumatism, vol. 36, no. 4, pp. 203–209, 2007. View at Publisher · View at Google Scholar · View at Scopus
  35. J. L. Cavalcante, J. A. Lima, A. Redheuil, and M. H. Al-Mallah, “Aortic stiffness: current understanding and future directions,” Journal of the American College of Cardiology, vol. 57, no. 14, pp. 1511–1522, 2011.
  36. C. Vlachopoulos, K. Aznaouridis, and C. Stefanadis, “Prediction of cardiovascular events and all-cause mortality with arterial stiffness. A systematic review and meta-analysis,” Journal of the American College of Cardiology, vol. 55, no. 13, pp. 1318–1327, 2010. View at Publisher · View at Google Scholar · View at Scopus
  37. L. Costa, F. Caso, L. D'Elia et al., “Psoriatic arthritis is associated with increased arterial stiffness in the absence of known cardiovascular risk factors: a case control study,” Clinical Rheumatology, vol. 31, no. 4, pp. 711–715, 2012. View at Publisher · View at Google Scholar
  38. C. Gonzalez-Juanatey, E. Amigo-Diaz, J. A. Miranda-Filloy et al., “Lack of Echocardiographic and Doppler Abnormalities in Psoriatic Arthritis Patients Without Clinically Evident Cardiovascular Disease or Classic Atherosclerosis Risk Factors,” Seminars in Arthritis and Rheumatism, vol. 35, no. 5, pp. 333–339, 2006. View at Publisher · View at Google Scholar · View at Scopus
  39. J. Feld, G. Weiss, I. Rosner et al., “Electrocardiographic findings in psoriatic arthritis: a case-controlled study,” Journal of Rheumatology, vol. 35, no. 12, pp. 2379–2382, 2008. View at Publisher · View at Google Scholar · View at Scopus
  40. Q. Shang, L.-S. Tam, G. W.-K. Yip et al., “High prevalence of subclinical left ventricular dysfunction in patients with psoriatic arthritis,” Journal of Rheumatology, vol. 38, no. 7, pp. 1363–1370, 2011. View at Publisher · View at Google Scholar
  41. A. Pines, M. Ehrenfeld, and E. Z. Fisman, “Mitral valve prolapse in psoriatic arthritis,” Archives of Internal Medicine, vol. 146, no. 7, pp. 1371–1373, 1986. View at Scopus
  42. J. L. Moya, M. Sanchez, M. D. Morales, and E. Brito, “Mitral valve prolapse (MVP) in psoriatic arthritis (PA),” Archives of Internal Medicine, vol. 147, no. 5, p. 992, 1987. View at Scopus
  43. L. S. Tam, B. Tomlinson, T. T. W. Chu et al., “Cardiovascular risk profile of patients with psoriatic arthritis compared to controls-the role of inflammation,” Rheumatology, vol. 47, no. 5, pp. 718–723, 2008. View at Publisher · View at Google Scholar · View at Scopus
  44. C. C. Mok, G. T.C. Ko, L. Y. Ho, K. L. Yu, P. T. Chan, and C. H. To, “Prevalence of atherosclerotic risk factors and the metabolic syndrome in patients with chronic inflammatory arthritis,” Arthritis Care and Research, vol. 63, no. 2, pp. 195–202, 2011. View at Publisher · View at Google Scholar
  45. D. H. Solomon, T. J. Love, C. Canning, and S. Schneeweiss, “Risk of diabetes among patients with rheumatoid arthritis, psoriatic arthritis and psoriasis,” Annals of the Rheumatic Diseases, vol. 69, no. 12, pp. 2114–2117, 2010. View at Publisher · View at Google Scholar · View at Scopus
  46. S. A. Mazlan, M. S. bin Mohamed Said, H. Hussein, K. binti Shamsuddin, S. A. Shah, and H. Basri, “A study of intima media thickness and their cardiovascular risk factors in patients with psoriatic arthritis,” Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové, vol. 52, no. 3, pp. 107–116, 2009. View at Scopus
  47. L. Eder, D. Zisman, M. Barzilai et al., “Subclinical atherosclerosis in psoriatic arthritis: a case-control study,” Journal of Rheumatology, vol. 35, no. 5, pp. 877–882, 2008. View at Scopus
  48. S. K. Raychaudhuri, S. Chatterjee, C. Nguyen, M. Kaur, I. Jialal, and S. P. Raychaudhuri, “Increased prevalence of the metabolic syndrome in patients with psoriatic arthritis,” Metabolic Syndrome and Related Disorders, vol. 8, no. 4, pp. 331–334, 2010. View at Publisher · View at Google Scholar · View at Scopus
  49. K. G. M. M. Alberti, R. H. Eckel, S. M. Grundy et al., “Harmonizing the metabolic syndrome: a joint interim statement of the international diabetes federation task force on epidemiology and prevention; National heart, lung, and blood institute; American heart association; World heart federation; International atherosclerosis society; And international association for the study of obesity,” Circulation, vol. 120, no. 16, pp. 1640–1645, 2009. View at Publisher · View at Google Scholar · View at Scopus
  50. S. M. Jones, C. P. D. Harris, J. Lloyd, C. A. Stirling, J. P. D. Reckless, and N. J. McHugh, “Lipoproteins and their subfractions in psoriatic arthritis: identification of an atherogenic profile with active joint disease,” Annals of the Rheumatic Diseases, vol. 59, no. 11, pp. 904–909, 2000. View at Publisher · View at Google Scholar · View at Scopus
  51. A. H. Skoczyñska, B. Turczyn, M. Barancewicz-Losek, and H. Martynowicz, “High-density lipoprotein cholesterol in patients with psoriatic arthritis,” Journal of the European Academy of Dermatology and Venereology, vol. 17, no. 3, pp. 362–363, 2003. View at Publisher · View at Google Scholar · View at Scopus
  52. F. Oliviero, P. Sfriso, G. Baldo et al., “Apolipoprotein A-I and cholesterol in synovial fluid of patients with rheumatoid arthritis, psoriatic arthritis and osteoarthritis,” Clinical and Experimental Rheumatology, vol. 27, no. 1, pp. 79–83, 2009. View at Scopus
  53. G. K. Hansson, “Mechanisms of disease: inflammation, atherosclerosis, and coronary artery disease,” New England Journal of Medicine, vol. 352, no. 16, pp. 1685–1695, 2005. View at Publisher · View at Google Scholar · View at Scopus
  54. J. T. Willerson and P. M. Ridker, “Inflammation as a cardiovascular risk factor,” Circulation, vol. 109, no. 21, pp. II2–II10, 2004. View at Scopus
  55. J. Danesh, J. G. Wheeler, G. M. Hirschfield et al., “C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease,” New England Journal of Medicine, vol. 350, no. 14, pp. 1387–1397, 2004. View at Publisher · View at Google Scholar · View at Scopus
  56. S. Thalmann and C. A. Meier, “Local adipose tissue depots as cardiovascular risk factors,” Cardiovascular Research, vol. 75, no. 4, pp. 690–701, 2007. View at Publisher · View at Google Scholar · View at Scopus
  57. S. Kaur, K. Zilmer, V. Leping, and M. Zilmer, “The levels of adiponectin and leptin and their relation to other markers of cardiovascular risk in patients with psoriasis,” Journal of the European Academy of Dermatology and Venereology, vol. 25, no. 11, pp. 1328–1333, 2011. View at Publisher · View at Google Scholar
  58. M. Anderssohn, E. Schwedhelm, N. Lüneburg, R. S. Vasan, and R. H. Böger, “Asymmetric dimethylarginine as a mediator of vascular dysfunction and a marker of cardiovascular disease and mortality: an intriguing interaction with diabetes mellitus,” Diabetes and Vascular Disease Research, vol. 7, no. 2, pp. 105–118, 2010. View at Publisher · View at Google Scholar · View at Scopus
  59. R. H. Böger, “Asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, explains the “L-arginine paradox” and acts as a novel cardiovascular risk factor,” Journal of Nutrition, vol. 134, no. 10, 2004. View at Scopus
  60. R. Schnabel, S. Blankenberg, E. Lubos et al., “Asymmetric dimethylarginine and the risk of cardiovascular events and death in patients with coronary artery disease: results from the AtheroGene Study,” Circulation Research, vol. 97, no. 5, pp. e53–59, 2005. View at Scopus
  61. T. M. Lu, Y. A. Ding, S. J. Lin, W. S. Lee, and H. C. Tai, “Plasma levels of asymmetrical dimethylarginine and adverse cardiovascular events after percutaneous coronary intervention,” European Heart Journal, vol. 24, no. 21, pp. 1912–1919, 2003. View at Publisher · View at Google Scholar · View at Scopus
  62. K. Krzyzanowska, F. Mittermayer, M. Wolzt, and G. Schernthaner, “Asymmetric dimethylarginine predicts cardiovascular events in patients with type 2 diabetes,” Diabetes Care, vol. 30, no. 7, pp. 1834–1839, 2007. View at Publisher · View at Google Scholar · View at Scopus
  63. T. Dziedzic, “Clinical significance of acute phase reaction in stroke patients,” Frontiers in Bioscience, vol. 13, no. 8, pp. 2922–2927, 2008. View at Publisher · View at Google Scholar · View at Scopus
  64. L. M. Graham, L. E. Daly, H. M. Refsum et al., “Plasma homocysteine as a risk factor for vascular disease: the European Concerted Action Project,” Journal of the American Medical Association, vol. 277, no. 22, pp. 1775–1781, 1997. View at Scopus
  65. R. Segal, Y. Baumoehl, O. Elkayam et al., “Anemia, serum vitamin B12, and folic acid in patients with rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus,” Rheumatology International, vol. 24, no. 1, pp. 14–19, 2004. View at Publisher · View at Google Scholar · View at Scopus
  66. M. A. Gonzalez-Gay, C. Gonzalez-Juanatey, T. R. Vazquez-Rodriguez et al., “Asymptomatic hyperuricemia and serum uric acid concentration correlate with subclinical atherosclerosis in psoriatic arthritis patients without clinically evident cardiovascular disease,” Seminars in Arthritis and Rheumatism, vol. 39, no. 3, pp. 157–162, 2009. View at Publisher · View at Google Scholar · View at Scopus
  67. P. M. Kearney, C. Baigent, J. Godwin, H. Halls, J. R. Emberson, and C. Patrono, “Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials,” British Medical Journal, vol. 332, no. 7553, pp. 1302–1305, 2006. View at Scopus
  68. E. Cauza, K. Cauza, U. Hanusch-Enserer, M. Etemad, A. Dunky, and K. Kostner, “Intravenous anti TNF-α antibody therapy leads to elevated triglyceride and reduced HDL-cholesterol levels in patients with rheumatoid and psoriatic arthritis,” Wiener Klinische Wochenschrift, vol. 114, no. 23-24, pp. 1004–1007, 2002. View at Scopus
  69. K. R. Castro, N. E. Aikawa, C. G. Saad et al., “Infliximab induces increase in triglyceride levels in psoriatic arthritis patients,” Clinical and Developmental Immunology, vol. 2011, Article ID 352686, 5 pages, 2011. View at Publisher · View at Google Scholar
  70. E. Spanakis, P. Sidiropoulos, J. Papadakis et al., “Modest but sustained increase of serum high density lipoprotein cholesterol levels in patients with inflammatory arthritides treated with infliximab,” Journal of Rheumatology, vol. 33, no. 12, pp. 2440–2446, 2006. View at Scopus
  71. K. Briot, P. Garnero, A. Le Henanff, M. Dougados, and C. Roux, “Body weight, body composition, and bone turnover changes in patients with spondyloarthropathy receiving anti-tumour necrosis factor α treatment,” Annals of the Rheumatic Diseases, vol. 64, no. 8, pp. 1137–1140, 2005. View at Publisher · View at Google Scholar · View at Scopus
  72. N. Sattar, P. Crompton, L. Cherry, D. Kane, G. Lowe, and I. B. McInnes, “Effects of tumor necrosis factor blockade on cardiovascular risk factors in psoriatic arthritis: a double-blind, placebo-controlled study,” Arthritis and Rheumatism, vol. 56, no. 3, pp. 831–839, 2007. View at Publisher · View at Google Scholar · View at Scopus
  73. M. J. L. Peters, P. Watt, L. Cherry et al., “Lack of effect of TNFα blockade therapy on circulating adiponectin levels in patients with autoimmune disease: results from two independent prospective studies,” Annals of the Rheumatic Diseases, vol. 69, no. 9, pp. 1687–1690, 2010. View at Publisher · View at Google Scholar · View at Scopus
  74. M. di Minno, S. Iervolino, R. Peluso, R. Scarpa, and G. di Minno, “Carotid intima-media thickness in psoriatic arthritis: differences between tumor necrosis factor-α blockers and traditional disease-modifying antirheumatic drugs,” Arteriosclerosis, Thrombosis, and Vascular Biology, 2011. View at Publisher · View at Google Scholar · View at Scopus
  75. L.-S. Tam, E. K. Li, Q. Shang et al., “Tumour necrosis factor alpha blockade is associated with sustained regression of carotid intima-media thickness for patients with active psoriatic arthritis: a 2-year pilot study,” Annals of the Rheumatic Diseases, vol. 70, no. 4, pp. 705–706, 2011. View at Publisher · View at Google Scholar
  76. K. Angel, S. A. Provan, H. L. Gulseth, P. Mowinckel, T. K. Kvien, and D. Atar, “Tumor necrosis factor-α antagonists improve aortic stiffness in patients with inflammatory arthropathies: a controlled study,” Hypertension, vol. 55, no. 2, pp. 333–338, 2010. View at Publisher · View at Google Scholar · View at Scopus
  77. K. Angel, S. A. Provan, H. B. Hammer, P. Mowinckel, T. K. Kvien, and D. Atar, “Changes in arterial stiffness during continued infliximab treatment in patients with inflammatory arthropathies,” Fundamental and Clinical Pharmacology, vol. 25, no. 4, pp. 511–517, 2011. View at Publisher · View at Google Scholar
  78. G. Mazzoccoli, I. Notarsanto, G. D. de Pinto et al., “Anti-tumor necrosis factor-α therapy and changes of flow-mediated vasodilatation in psoriatic and rheumatoid arthritis patients,” Internal and Emergency Medicine, vol. 5, no. 6, pp. 495–500, 2010. View at Publisher · View at Google Scholar · View at Scopus
  79. M. J. L. Peters, D. P. M. Symmons, D. McCarey et al., “EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis,” Annals of the Rheumatic Diseases, vol. 69, no. 2, pp. 325–331, 2010. View at Publisher · View at Google Scholar · View at Scopus
  80. A. Beswick and P. Brindle, “Risk scoring in the assessment of cardiovascular risk,” Current Opinion in Lipidology, vol. 17, no. 4, pp. 375–386, 2006. View at Publisher · View at Google Scholar · View at Scopus
  81. R. M. Conroy, K. Pyörälä, A. P. Fitzgerald et al., “Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project,” European Heart Journal, vol. 24, no. 11, pp. 987–1003, 2003. View at Publisher · View at Google Scholar · View at Scopus