Serum Immunoglobulin Free Light Chain Assessment in IgG4-Related Disease

Table 1

Patients’ characteristics.

𝑁	Age,; gender	IgG4-RD organ; involvement	𝜅 FLC; mg/L	𝜆 FLC; mg/L	𝜅/𝜆 ratio	GFR	Disease; status
1*	84, M	RPF, mesenteric IPT, lung, LN	59.85	29.63	2.02	—	A
2	71, M	Kidney, LN, pancreas, biliary tree, prostate	41.97	29.31	1.43	39	A
3	63, M	RPF, AIP, sclerosing cholangitis, sialadenitis, renal IPT, LN, periaortitis, pleura/lung	49.8	24.54	2.02	—	A
4	71, M	RPF, aortitis, dacryoadenitis, sialadenitis, LN	27.55	47.2	0.58	—	A
5*	59, M	RPF, aortitis, carotidal and iliac arteritis, LN, hypophysitis	30.48	9.48	3.21	—	A
6*	74, M	AIP, orbital IPT, sialadenitis, sclerosing cholangitis, sclerosing cholecystitis, TIN	12.44	12.3	1.01	—	A
7	75, M	AIP, LN, TIN, sialadenitis, pleura/lung	2610	511	5.11	12	A
8	63, M	Meningeal IPT	20.9	18.4	1.14	—	A
9	67, M	Periaortitis	20.39	12.46	1.63	—	A
10	65, M	AIP	61.85	65	0.95	—	A
11	58, F	Pulmonary IPT	20.14	16.19	1.24	—	A
12	27, M	AIP, sclerosing cholangitis, LN	219.62	33.24	6.6	—	A
13	80, M	Sialadenitis, TIN, LN, lung	1501	312	4.84	6	A
14	62, M	Parotid IPT, LN	13.8	13	1.06	—	A
15	76, M	RPF, LN	46.2	22.1	2.09	—	A
16	84, M	TIN, LN, PAI, RPF, sialadenitis	97.3	79.42	1.22	67	NA
		Mean**	315.7	77.06
		Median**	41.97	24.54	1.63
		IQR**	(20.39–61.85)	(13–47.2)	(1.06–3.2)

Values in bold are normal values.
∗Patients from which samples were analyzed two times (in active and nonactive disease). Given values in the table are values during active disease, **given values for mean, median and IQR are calculated with values obtained in patients with active disease (patient no. 16 is excluded). AIP: autoimmune pancreatitis; IPT: inflammatory pseudotumor: LN: lymph nodes; RPF: retroperitoneal fibrosis; TIN: tubulointerstitial nephritis; GFR: glomerular filtration rate (mL/min/1.73 m²). Disease status: A: active, NA: nonactive.