Clinical Study

Validation of a Prediction Rule for the Diagnosis of Rheumatoid Arthritis in Patients with Recent Onset Undifferentiated Arthritis

Table 1

General characteristic of total population and by sex.

CharacteristicTotal ( )Females ( ; 74 %)Males ( ; 26 %) value (females versus males)

Age, mean (SD)55.6 (17.4)54.6 (18.1)58.5 (15)0.3459
Smoking status, (%)
 Never smoked61 (69.3)49 (75.4)(52.2)
 Smoked in the past(21.6)9 (13.8)(43.4)0.011
 Still smoking(9.1)7 (10.8)(4.4)
HAQ, mean (SD)1.1 (1.2)1.2 (1.3)0.9 (0.6)0.3418
Number of tender joints, mean (SD)6.8 (5)6.6 (4.6)7.4 (6.2)0.4800
Number of swollen joints, mean (SD)5.5 (4.2)5.3 (3.8)6.1 (5.1)0.4089
Disease duration, (months) mean (SD)3.6 (4.3)3.9 (4.8)2.9 (2.1)0.3118
VAS pain, (mm) mean (SD)59.9 (26.5)58.9 (26.5)62.7 (18.1)0.5245
VAS patients global, (mm) mean (SD)56.5 (25.6)55.5 (26.6)59.3 (23.1)0.5427
VAS physician global, (mm) mean (SD)41.6 (21.5)41.3 (22.4)42.4 (19.6)0.8292
VAS morning stiffness, (mm) mean (SD)49.8 (30.9)49.5 (31.5)50.5 (29.8)0.8875
ESR, mean (SD)36.9 (25)35 (22.8)42.3 (30.3)0.2193
PCR, mean (SD)15.7 (21.2)13.1 (20.9)21.8 (21)0.1222
Positive RF: (%)27 (30)21 (31)6 (25)0.559
Positive anti-CCP: (%)47 (51.6)38 (57)9 (37.5)0.106
DAS28 (SD)5.2 (1.2)5.1 (1.2)5.3 (1.2)0.6708
van der Helm score, mean (SD)6.9 (2)7.1 (2.1)6.1 (1.8)0.0380
Mean ACR/EULAR criteria (SD)5.1 (2.1)5.1 (2.2)5.1 (2)0.9263

SD: standard deviation; HAQ: Health Assessment Questionnaire, VAS: visual analogue scale; ESR: eritrosedimentation rate; PCR: C-reactive protein; DAS28: disease activities score 28 joints,; RF: rheumatoid factor; CCP: cyclic citrullinated peptide.