Design of the Tocilizumab in Giant Cell Arteritis Trial

Table 3

Standardized prednisone-taper protocols during GiACTA.

Weeks	Daily prednisone dose (mg) 26-week taper	Daily prednisone dose (mg) 52-week taper
1	60	60
2	50	50
3	40	40
4	35	35
5	30	30
6	25	25
7	20	20
After week 7, the CS dosing will be double-blinded
8	15	17.5
9	12.5	17.5
10	12.5	15
11	10	15
12	9	12.5
13	8	10
14	7	10
15	6	10
16	6	10
17	5	9
18	5	9
19	4	9
20	4	9
21	3	8
22	3	8
23	2	8
24	2	8
25	1	7
26	1	7
27	CS placebo	7
28	CS placebo	7
29	CS placebo	6
30	CS placebo	6
31	CS placebo	6
32	CS placebo	6
33	CS placebo	5
34	CS placebo	5
35	CS placebo	5
36	CS placebo	5
37	CS placebo	4
38	CS placebo	4
39	CS placebo	4
40	CS placebo	4
41	CS placebo	3
42	CS placebo	3
43	CS placebo	3
44	CS placebo	3
45	CS placebo	2
46	CS placebo	2
47	CS placebo	2
48	CS placebo	2
49	CS placebo	1
50	CS placebo	1
51	CS placebo	1
52	CS placebo	1