Clinical Study

The Relationship between Mechanical Hyperalgesia Assessed by Manual Tender Point Examination and Disease Severity in Patients with Chronic Widespread Pain: A Cross-Sectional Study

Figure 1

Number of significant covariates versus tender point count (TPC) thresholds, varying between 1 and 17 and with the pain response cutoff set at 2 at the tender point examination. Analyzed in the univariate/marginal model a large number of variables linked to pain and pain-related functional interference (summarized in Table 4) appeared as consistently significant explanatory factors from a TPC threshold at 8, indicating a perturbation of clinical disease severity at this threshold.
417596.fig.001