Development and Implementation of a Double-Blind Corticosteroid-Tapering Regimen for a Clinical Trial

Figure 3

(a) Final prednisone wallets developed and approved for the GiACTA study. (b) Illustration of the use of placebo capsules to ensure blinding. Two separate weeks from the six- and 12-week prednisone tapering regimens are shown. Placebo capsules are used to ensure that patients receive an equal number of capsules across both regimens, thus ensuring blinding. PBO: placebo.

(a)

(b)