Review Article

Gastric Antral Vascular Ectasia in Systemic Sclerosis: Current Concepts

Table 1

Prevalence of GAVE in patients with systemic sclerosis.

ReferenceCohort characteristicsPrevalence of GAVEOther variables measured

Ghrénassia et al. [18]Patients from European League Against Rheumatism Scleroderma Trials and Research.
49 patients were included (24 with diffuse cutaneous SSc).
1%Diminished DLCO value.
Presence of anti-RNA-polymerase III antibodies.
Higher association with anemia.

Hung et al. [15]Patients from Scleroderma: Cyclophosphamide Or Transplant (SCOT) trial.
103 patients diagnosed by endoscopy.
22.3%No association between anti-RNA polymerase III and GAVE.
Presence of vascular ectasia in other parts of the stomach.

Ingraham et al. [19]Patients from the Division of Rheumatology at Georgetown University and Thomas Jefferson University. 28 patients, 17 with diffuse cutaneous and 11 with limited cutaneous systemic sclerosis.4% of patients had anti-topoisomerase I antibody.

Marie et al. [14]264 patients with systemic sclerosis between 1900 and 2008.5.7%Systemic sclerosis onset preceded watermelon stomach manifestations in 13 patients (86.7%).

Patients with diffuse cutaneous systemic sclerosis within 18 months of the first symptoms.