Effect of Curcuma xanthorrhiza Supplementation on Systemic Lupus Erythematosus Patients with Hypovitamin D Which Were Given Vitamin D₃ towards Disease Activity (SLEDAI), IL-6, and TGF-β1 Serum

Table 3

Effects of C. xanthorrhiza supplementation on vitamin D₃ administration towards cytokine levels.

Variable	Vitamin D3 + placebo ()			Vitamin D3 + Curcuma xanthorrhiza ()
	Pre	Post	value	Pre	Post	value
IL-6 (pg/ml)	12.7	3.6	0.001	6.8	5.2	0.013	0.061
	(IQR: 6.6–18,1)	(IQR: 2.6–4.8)		(IQR: 4.7–15.4)	(IQR: 3.2–6.4)
TGF-β1 (pg/ml)	289.9	355.9	0.000	279.3	348.4	0.011	0.261
	(IQR: 248.8–341.9)	(IQR: 328.8–427.1)		(IQR: 249.4–313.1)	(IQR: 292.1–4386.8)
TGF-β1/IL-6 (pg/ml)	35.2 ± 22.3	78.6 ± 48.7	0.003	30.5 ± 18.1	115.6 ± 58.0	0.000	0.038

= differential test of the effects of Curcuma xanthorrhiza supplementation after treatment in both groups, expressed by . There is a significant difference (); IQR: interquartile.