Clinically Recognized Depression and Mental Health Treatment in a Single Center Cohort of Patients with Systemic Sclerosis

Table 3

Associations of SSc symptom burden and COVID-19 pandemic with CESD-R score.

Characteristic	CESD-R score
	Beta coefficient (confidence interval)
Baseline dyspnea index	2.7 (1.5-3.8)	<0.01
UCLA SCTC GIT 2.0 total score	9.5 (4.8-14.1)	<0.01
UCLA SCTC GIT 2.0 reflux subscale	7.1 (2.5-11.8)	<0.01
UCLA SCTC GIT 2.0 distension/bloating	4.1 (1.4-6.8)	<0.01
UCLA SCTC GIT 2.0 diarrhea^‡	6.3 (2.8-9.9)	<0.01
UCLA SCTC GIT 2.0 fecal soilage	5.0 (0.1-9.9)	0.05
UCLA SCTC GIT 2.0 constipation	2.6 (-0.7-5.9)	0.11
UCLA SCTC GIT 2.0 emotional well-being	6.9 (2.7-11.1)	<0.01
UCLA SCTC GIT 2.0 social function^‡	10.2 (5.1-15.3)	<0.01
Raynaud’s condition score	0.8 (-0.1-1.7)	0.09
Modified Rodnan skin score	0.4 (0.1-0.6)	<0.01
Timepoint pre versus during COVID-19 pandemic	0.8 (-4.7-6.3)	0.76

Quantile regression models comparing median values, adjusted for age, gender, and disease duration since first non-Raynaud’s symptoms. 128 participants included in each model unless otherwise indicated. Missing dyspnea index data from 62 participants, . Missing data from 1 participant, . ‡Missing data from 2 participants, .