Resolution of Ternary Mixture of Aspirin, Atorvastatin, and Clopidogrel by Chemometric-Assisted UV Spectroscopic and Liquid Chromatography Methods

Table 1

Recovery data obtained for different synthetic mixtures by using the HPSAM method with simultaneous addition of three analytes.

Mixture No.	ASP			ATOR			CLOP
	Added (µg)	Found (µg)	Recovery%	Added	Found	Recovery%	Added	Found	Recovery%
1	2.5	2.488	99.5	7.5	7.501	100.0	5.0	4.987	99.7
2	5.0	5.005	100.1	7.5	7.303	97.4	5.0	4.891	97.8
3	7.5	7.444	99.3	7.5	7.499	99.9	5.0	5.015	100.3
4	10.0	9.92	99.2	7.5	7.511	100.1	5.0	5.010	100.2
5	15.0	14.66	97.7	7.5	7.407	98.8	5.0	5.065	101.3
6	20.0	20.04	100.2	7.50	7.505	100.1	5.0	5.080	101.6
			𝑥 = 99.3; RSD = 0.92
1	10.0	10.12	101.2	2.5	2.509	100.4	5.0	5.035	100.7
2	10.0	10.08	100.8	5.0	4.999	100.0	5.0	5.090	101.8
3	10.0	9.92	99.2	7.5	7.611	101.5	5.0	5.010	100.2
4	10.0	9.75	97.5	10.0	9.85	98.5	5.0	4.888	97.8
5	10.0	9.96	99.6	12.5	12.22	97.8	5.0	4.921	98.4
6	10.0	10.0	100.0	17.5	17.34	99.1	5.0	4.999	100.0
						𝑥 = 99.6; RSD = 1.35
1	10.0	10.31	103.1	7.5	7.438	99.2	2.5	2.486	99.4
2	10.0	9.92	99.2	7.5	7.511	100.1	5.0	5.010	100.2
3	10.0	10.22	102.2	7.5	7.502	100.0	7.5	7.333	97.8
4	10.0	9.86	98.6	7.5	7.547	100.6	10.0	10.22	102.2
5	10.0	9.99	99.9	7.5	7.444	99.2	15.0	13.03	100.2
6	10.0	9.97	99.7	7.5	7.400	98.7	20.0	19.90	99.5
									𝑥 = 99.9; RSD = 1.43