Review Article

Selective Inguinal Lymphadenectomy in the Treatment of Invasive Squamous Cell Carcinoma of the Vulva

Table 1

FIGO staging of invasive cancer of the vulva.

Stage ITumor confined to the vulva
IALesions ≤2 cm in size confined to the vulva or perineum and with stromal invasion ≤1.0 mm*, no nodal metastasis
IBLesions >2 cm in size confined to the vulva or perineum with stromal invasion greater than 1.0 mm*, no nodal metastasis

Stage IITumor of any size with extension to adjacent perineal structures (1/3 lower urethra, 1/3 lower vagina, anus), no nodal metastasis

Stage IIITumor of any size with or without extension to adjacent perineal structures (1/3 lower urethra, 1/3 lower vagina, anus) with positive inguinofemoral lymph nodes
 IIIAWith 1 lymph node metastasis (≥5 mm),
 IIIB(i) With 2 or more lymph node metastases (≥5 mm),
(ii) 3 or more lymph node metastases (<5 mm)
 IIICWith positive nodes with extracapsular spread

Stage IVTumor invades other regional (2/3 upper urethra, 2/3 upper vagina) or distant structures
 IVATumor invades any of the following:
(i) Upper urethra and/or vaginal mucosa, bladder mucosa, rectal mucosa, or fixed to pelvic bone,
(ii) Fixed or ulcerated inguinofemoral lymph nodes
 IVBAny distant metastasis including pelvic lymph nodes

*The depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion.