Table 1: Clinicopathologic characteristics of hereditary versus sporadic breast and ovarian cancer.

Breast cancerOvarian cancer

Average age of diagnosisBRCA1 BRCA1
BRCA2 BRCA2

Pathological features differentiation grade, stage
↑ bilateral tumours? ↑ papillary serous serology
↑ # lymph nodes

Receptor statusBRCA1: ↑ ER−/PR−/HER2−
BRCA2: similar to sporadic tumours

Survival progression free-survival↑ progression-free survival
overall survival↑ overall survival