Clinical Study

Reoperation following Pancreaticoduodenectomy

Table 2

Univariate analysis of factors predicting the need for early reoperation.

ParametersEarly reoperations ( 𝑁 = 7 8 )Not reoperated early ( 𝑁 = 4 4 2 )P value

Age in years (median) 5251.5 0.850
Gender (M/F) 53/25318/124 0.498
Duration of jaundice > 3 months 21 (27%) 69 (15.6%)0.051
Comorbidities 17 (21.8%)111 (25.1%)0.572
Preoperative hemoglobin (median)11.011.20.425
Preoperative albumin
(median)
3.53.50.643
Total bilirubin > 10 mg%18 (23.1%) 51 (11.5%)0.010
Preoperative biliary drainage41 (52.6%)
276 (62.4%)0.103
Duration of surgery (hours)7.357.00.096
Blood loss (mL) (median)750 mL500 mL0.001
Blood transfusion50 (64.1%)213 (48.2%)0.010
 Malignancy (94%)Malignancy (93%)0.844
Pathology Ampullary Ca (74%) Ampullary Ca (71%)
 Benign (6%)  Benign (7%)
PPH67.9%9.3%0.000
PEA leak34.6%14.3%0.001
HJ leak24.3%6.3%0.000
DJ/GJ leak14.1%2.5%0.000
DGE21.8%10.2%0.007
Intraabdominal collection43.6%10.2%0.000
ARF11.5%1.6%0.000
Septicemia32%6.3%0.000
Postoperative hospital stay (Mean)25.5 days13 days0.000
In-hospital mortality26 (33.1%)16 (3.6%)0.000

PPH: post pancreatectomy hemorrhage; PEA: pancreaticoenteric anastamosis; HJ: hepaticojejunostomy; DJ: duodenojejunostomy; GJ: gastrojejunostomy; DGE: delayed gastric emptying; ARF: acute renal failure.