Increasing Age Is Associated with Worse Prognostic Factors and Increased Distant Recurrences despite Fewer Sentinel Lymph Node Positives in Melanoma

Table 2

Multivariable analysis of overall survival, using age by continuous variable and by decade.

(a)

Variable	Hazard ratio	95% confidence interval	P value
SLN POS	4.8	3.35–6.87	<0.001
Male	1.5	1.07–2.20	0.02
Age (continuous)	1.02	1.01–1.03	0.02
Breslow depth (≥1 mm)	2.9	1.15–7.35	0.03
Ulceration	2.24	1.58–3.16	<0.001
Head and neck site	3.07	2.09–4.51	<0.001

(b)

Variable	Hazard ratio	95% confidence interval	P value
SLN POS	4.78	3.34–6.86	<0.001
Male	1.51	1.05–2.17	0.02
Age
<30 versus 31–40 yrs	1.56	0.70–3.56	0.28
<30 versus 41–50 yrs	1.36	0.63–2.94	0.44
<30 versus 51–60 yrs	2.07	0.99–4.33	0.05
<30 versus ≥61 yrs	2.68	1.31–5.47	0.01
Breslow depth (≥1 mm)	2.97	1.17–7.52	0.02
Ulceration	2.27	1.61–3.22	<0.001
Head and neck site	3.06	2.07–4.51	<0.001