Review Article
Radiotherapy after Conservative Surgery in Ductal Carcinoma In Situ of the Breast: A Review
Table 1
Characteristics of the prospective randomized trials.
| | NSABP-B17 | EORTC 10853 | SweDCIS | UK/ANZ DCIS |
| Entry dates | 1985–1990 | 1986–1996 | 1987–1999 | 1990–1998 | Pts. randomized | 818 | 1010 | 1067 | 1030 | CS | 405 | 503 | 533 | 508 | CS + RT | 413 | 510 | 534 | 522 | Mammographic detection | 80.4% | 71% | 78.7% | NS | Central pathological review | 76% | 85% | 26% | 0% | Negative margins required | Yes | Yes | No | Yes | Margins free | 78% | 83% | 80% | 100% | RT dose | 50 Gy/25 fr. | 50 Gy/25 fr. | 50–54 Gy/25–27 fr. | 50 Gy/25 fr. | Boost | 10 Gy/5 fr. (9% of pts.) | 10 Gy/5 fr. (5% of pts.) | NR | NR |
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Legend: Pts: patients; NS: not specified; NR: not recommended; RT: radiotherapy; CS: conservative surgery; fr.: fractions.
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