Review Article

Radiotherapy after Conservative Surgery in Ductal Carcinoma In Situ of the Breast: A Review

Table 2

Comparison of breast cancer events in prospective randomized trials.

NSABP-B17 (17.25 yrs. median FU) EORTC 10853 (10.5 yrs. median FU) SweDCIS (8.4 yrs. mean FU) UK/ANZ DCIS (12.7 yrs. median FU)
CS %CS + RT%CS%CS + RT%CS%CS + RT%CS%CS + RT%

Ipsilateral events
 Total35.019.826.015.027.112.119.4 7.1
 Invasive19.610.713.0 8.012.3 7.29.1 3.3
 In situ15.4 9.014.0 7.014.8 4.99.7 3.8
Contralateral events7.9 9.3 4.0 8.05.9 6.54.1 3.3
OS%86*87*959590**92**97.9#96.2#

*At 12 yrs. followup.
**Breast cancer deaths and other deaths are reported in the study.
#All trial participants included.
Legend: yrs.: years; FU: followup; OS: overall survival; RT: radiotherapy; CS: conservative surgery.