Radiotherapy after Conservative Surgery in Ductal Carcinoma In Situ of the Breast: A Review

Table 3

The influence of the boost on local control.

Studies	N. of pts.	Median age (y)	Positive margins %	Necrosis %	Median FU (months)	LR %
Omlin et al. [31]
Boost	150	41*	7	32	72	14**
No boost	166		4	41		28**
Yerushalmi et al. [32]
Boost	20	58	/	/	81	15
No boost	55	/	/	/		12.7
Julian  et al. [33]
Boost	692	53	21	52	168	13.8
No boost	877		15	45		14.3
Monteau et al. [34]
Boost	147	53	50	60	89	9.3^∧
No boost	55		74	64		9.6^∧
Wai et al. [35]
Boost	144	56	29	46	112	9*
No boost	338	55	12	55		6*
Wong et al. [44]
Boost	79	58	5	56	46	0
No boost	121		0.8	49		6

*All < 45 years, **10-year LR, ^∧7-year LR, ^#Reexcision for close (<2 mm) margins.
Legend: pts.: patients; (y): years; FU: follow up; LR: local recurrence.