Sellar and Parasellar Metastatic Tumors

Table 1

Clinical, endocrine, and radiological features of 6 patients with metastatic tumors of the sellar/parasellar region.

Patient	Age	Sex	Presenting symptoms	Symptom duration	Primary disease	Metastatic lesion	Location	Management	Outcome
1	77	m	Retroorbital pain; Left nerve III palsy	4 months	Prostate cancer	Prostate cancer	CS and sella extending to inferior orbital fissure and upper clivus	Transsphenoidal biopsy, radiotherapy, chemotherapy	Stable neurological findings at two months
2	82	f	Hearing loss; Facial pain; Numbness in cranial nerve V1, V2	Several weeks	Breast cancer	Breast cancer	Petrous apex extending to Meckel’s cave, lateral CS, and IAC	Transcranial biopsy, radiotherapy, chemotherapy	N/A
3*	79	m	Cranial nerve III and VI palsies	Several weeks	Prostate cancer	Melanoma	Bilateral CS, sella, clivus, and posterior nasal cavity	Transsphenoidal biopsy	N/A
4	21	m	Horner's syndrome; Facial pain	1 month	Osteosarcoma; Renal cell cancer	Renal cell cancer	CS extending to sphenoid sinus, pterygopalatine fossa, and optic canal	Radiation, chemotherapy	N/A
5	42	f	Gait instability; Headache	1 month	Unknown	Lymphoma	Sellar/suprasellar lesion with bilateral CS, medial sphenoid wing, and clivus involvement	Transsphenoidal biopsy, chemotherapy, possible radiotherapy	N/A
6	57	f	Decreased visual acuity; Peripheral vision defect	1 month	Breast cancer	Breast cancer	Greater sphenoid wing extending to the anterior clinoidal process with the optic nerve encasement	Transcranial decompression of optic nerve and the CS, radiotherapy with possible chemotherapy	Stable neurological findings and primary disease at one year

CS: cavernous sinus, IAC: internal acoustic canal, N/A: not available
*Patient was previously presented in McCutcheon et al.