Clinical Study

Intensity-Modulated Radiation Therapy for Rectal Carcinoma Can Reduce Treatment Breaks and Emergency Department Visits

Table 1

Patient characteristics.

Characteristic3DCRT ( )IMRT ( ) value

Mean age (years)56.352.70.23
Male/female ( ) (%)40/16 (71/29)15/15 (50/50)0.06
Total elapsed days (mean)40.538.70.081
Treatment suspended ( ) (%)11 (20%)0 (0)0.0002
Median total dose (cGy)504050400.23

Chemotherapy types ( ) (%)0.71
Capecitabine or 5-FU45 (80)27 (90)
Capecitabine/oxaliplatin7(12)3 (10)
Capecitabine/CPT-111 (2)0
5-FU/leucovorin/oxaliplatin3 (5)0

Preoperative T stage ( ) (%)0.85
 T201 (3)
 T351 (91)27 (90)
 T45 (9)2 (7)

Preoperative N stage ( ) (%)0.21
 N0/x26 (46)10 (33)
 N1/N230 (54)20 (67)

Preoperative M stage ( )%0.91
 M052 (93)27 (90)
 M14 (7)3 (10)

Pathological complete response (%)21%20%0.555
 Downstaging T stage (%)50600.26
 Downstaging N stage (%)34400.37