Research Article
Resection of Nonalcoholic Steatohepatitis-Associated Hepatocellular Carcinoma: A Western Experience
Table 4
Pathological data and longterm outcomes.
| Patient | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
| Tumor size (cm) | 5.1 | 1.8 | 6.2 | 6.0 | 4.5 | 6.3 | 19.0 | 6.0 | 8.4 | Number of nodules | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | Vascular invasion | None | None | Micro | None | Gross | Micro | Gross | Micro | Micro | Satellites | Yes | No | Yes | No | No | No | Yes | No | No | Tumor cell differentiationa | Well | Well | Well | Mod | Mod | Mod | Poor | Mod | Mod | Steatotic tumor cells | No | Yes | Yes | No | No | No | No | Yes | Yes | Parenchymal fibrosisb | F4 | F4 | F4 | F1 | F3 | F3 | F1 | F1 | F1 | Margin (mm) | 3 | 5 | 0 | 20 | 10 | 10 | 10 | 2 | 2 | Regional lymph nodes (+) | No | No | No | No | No | No | No | No | No | Metastases | No | No | No | No | No | No | Yes | No | No | Recurrence gg | Yes | Yes | Yes | No | Yes | Yes | No | Yes | Yes | Time to recurrence (months) | 19.4 | 6.4 | 8.3 | — | 6.2 | 37.9 | — | 6.2 | 16.8 | Distribution of 1st recurrence | IH | IH | IH | — | IH | IH | — | IH/EH | IH | Treatment of 1st recurrence | TACE | OLT | TACE | — | RR | RFA | — | RR | RFA | Survival (months) | 105.2 | 32.3 | 27.8 | 84.0 | 62.1 | 68.0 | 1.1 | 34.7 | 38.3 |
|
|
Micro: microscopic, Mod: moderate, IH: intrahepatic, EH: extrahepatic, TACE: transarterial chemoembolization, OLT: orthotopic liver transplant, RR: repeat resection, RFA: radiofrequency ablation.
aBased on Edmonson grading system, bbased on Brunt criteria.
|