Gastrointestinal Stromal Tumors Associated with Neurofibromatosis 1: A Single Centre Experience and Systematic Review of the Literature Including 252 Cases

Table 3

Comparison between GISTs presenting in NF1 patients and sporadic GISTs.

	GISTs in NF1 patients	GIST personal case series	𝑃 value
Age
Mean (years)	52.8	61.4	0.0001*
Sex
M/F ratio	1	1.61	0.2^§
Localization (%)
Stomach	5.4	56.9	<0.0001§
Jejunum/ileus	69.8	23.4
Other	24.8	19.7
Symptoms (%)
Incidental	52.5	19.1	0.002^§
Other	47.5	80.9
Diameter
Mean (cm)	3.8	7.4	0.0003*
Risk classification (%)
Low risk	64.9	41.3	0.03^§
Intermediate risk	17.5	21.7
High risk	17.5	37.0

^∗𝑡-test; §Chi-square test.