Fundus Autofluorescence Imaging in an Ocular Screening Program

Figure 2

(a, b) Compared to color, FAF imaging identified a larger number of dot-blot hemorrhages and microaneurysms and was superior at outlining RPE disturbances. (c, d) Perifoveal RPE hypopigmentation was evident on the color image, while extensive focal RPE defects were seen on FAF imaging. (e, f) FAF versus color imaging showed more detail in terms of the extent of RPE disturbance. (g, h) A faint circular lesion was seen nasal to the fovea on color imaging. FAF imaging was superior to color imaging at characterizing the full extent of this lesion by delineating RPE hyperfluorescence and damage. (i, j) Extensive fibrosis was appreciated on color imaging, while FAF imaging further delineated an extensive area of RPE degeneration. (k, l) Diabetic macular edema with extensive hard exudates were clearly identified on color but not FAF imaging.