The Mechanosensory Role of Primary Cilia in Vascular Hypertension

Figure 1

Mechanosensory cilia as microcompartments. Primary cilia are mechanosensory compartments that house many sensory proteins. Activation of these compartments through the sensory machineries will generate a cascade of various proteins activation, which results in nitric oxide production. CaM, calmodulin; PKC, calcium-dependent protein kinase; eNOS, endothelial nitric oxide synthase. Figure was adapted from [22].